Di Cesare Andrea

Permanent researcher

Other information

Broad research specialisms:

• Antibiotic resistance in the environment
• Relationship between antibiotic resistant and virulent environmental and clinical strains
• Horizontal Gene Transfer (HGT) in environmental strains

Qualifications:

2014: PhD Biomolecular Science, University of Ancona
2009: MSc Industrial Biotechnology, University of Urbino Career

Career:

2014-present: Postdoctoral fellow, CNR - Institute of Ecosystem Study, Verbania
2011-2014: PhD student Biomolecular Science, University of Ancona
2010: Research Fellow, IZSUM, Ancona

Research interests:

I work on the spread of antibiotic resistance at the molecular level in human gut, marine, and freshwater environments. My goal is to understand the role of antibiotic (AB) resistant strains/traits in natural bacterial communities, to evaluate HGT mechanisms, and to study the fitness cost AB-related accessories genes.

Research project:

Natural antibiotic resistances, and impact of AB on the resilience of the bacterial community

Publications:

• Epidemic Escherichia coli ST131 and Enterococcus faecium ST17 in coastal marine sediments from an Italian beach Environmental Science and Technology 2013 Dec 3;47(23):13772-80. Vignaroli C, Luna GM, Pasquaroli S, Di Cesare A, Petruzzella R, Paroncini P, Biavasco F.
• The marine environment as a reservoir of antibiotic-resistant and virulent enterococci strongly associated with clinical strains Environmental Microbiology Reports 2014 Apr 6;(2):184-90. Di Cesare A*, Pasquaroli S, Vignaroli C, Paroncini P, Luna GM, Manso E, Biavasco F.  
    * Corresponding Author
• Aquaculture can promote the presence and spread of antibiotic-resistant enterococci in marine sediments PLoS One 2013 Apr 26;8(4):e62838. Di Cesare A*, Luna GM, Vignaroli C, Pasquaroli S, Tota S, Paroncini P, Biavasco F 
    * Corresponding Author
• An extensive investigation into the prevalence and the genetic and serological diversity of toxigenic V. parahaemolyticus in Italian marine coastal waters Environmental Microbiology 2013 May;15(5):1377-1386. Ottaviani D, Leoni F, Rocchegiani E, Mioni R, Costa A, Virgilio S, Serracca L, Bove D, Canonico C, Di Cesare A, Masini L, Potenziani S, Caburlotto G, Ghidini V, Lleo MM.
• Antibiotic-resistant enterococci in seawater and sediments from a coastal fish farm. Microbial Drug Resistance 2012 Oct;18(5):502-509 Di Cesare A, Vignaroli C, Luna GM, Pasquaroli S, Biavasco F.
• New sequence types and multidrug resistance among pathogenic Escherichia coli isolates from coastal marine sediments. Applied Environmental Microbiology 2012 Jun;78(11):3916-3922 Vignaroli C, Luna GM, Rinaldi C, Di Cesare A, Danovaro R, Biavasco F.

Papers in preparation:

• Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to Enterococcus faecalis Submitted Pasquaroli S, Di Cesare A, Vignaroli C, Conti G, Citterio B, Biavasco F.
• Biofilm role in the protection of replicative form of Legionella pneumophila Submitted Andreozzi E, Di Cesare A, Sabatini L, Chessa E, Sisti D, Rocchi M, Citterio B.
• Antibiotic resistance transfer and macrophage killing by an Enterococcus faecium isolate from coastal marine sediment Submitted Sabatino R **, Di Cesare A **, Pasquaroli S, Vignaroli C, Larossa D, Rossi L, Magnani M, Brenciani A, Biavasco F.

**Co-first Author *Corresponding Author

Publications: